The logic vaccine can reduce the danger of dementia

Logical impetigo vaccination can reduce the risk of dementia, A large new study He finds.

The results provide some of the strongest evidence so far that some viral infections can have effects on brain function after years and that preventing them can help avoid cognitive decline.

The study, published on Wednesday in Nature, found that the people who received the logic vaccine were 20 percent less likely to develop dementia in the seven years after those who were not vaccinated.

“If you reduce the risk of dementia by 20 percent, this is very important in the context of public health, given that we do not have much at the present time that slows down the appearance of dementia,” said Dr. Paul Harrison, Professor of Psychiatry at Oxford. Dr. Harrison did not participate in the new study, but he did Other research This indicates that the logic vaccines are less than the risk of dementia.

Whether protection can last after only seven years with more research. But with a few treatments or effective protection currently, Dr. Harrison said, it seems that the logic vaccines are “some of the most powerful potential preventive monuments against the dementia that we know are useless in practice.”

Logical imbalances from the virus that causes childhood chickenpox and varicose veins stems, which usually remains sleeping in decades neurons. With the weakening of the age of people and their immune system, the virus can activate and cause logical images, with symptoms such as combustion, deception, painful pimples and numbness. Nerve pain can become chronic and disable.

In the United States, about One in three people Develop at least one case of logical images, which are also called Herpes Zoster, in their lives, the estimates of the centers of control and prevention of diseases. About a third of qualified adults has received the vaccine in recent years, According to the Center for Anti -Tennis and Combating

Several previous studies have indicated that the logic vaccine may reduce the risk of dementia, but most of them were unable to exclude the possibility that people who are vaccinated have other properties to protect against dementia, such as healthy lifestyles or the best diets or more years of education.

The new study ruled out many of these factors.

“It is a very strong evidence,” said Dr. Anoubam Gina, an economist at the Faculty of Medicine at the University of Harvard Medical College, who did not participate in the study but reviewed.

The study appeared by an unusual side of the shogy impermissibility in Wales on September 1, 2013. Welsh officials created a strict condition of age: the people who were in 79 years on that date were qualified to vaccinate for one year, but these 80 and over. With the age of 79 years of age, they became qualified to vaccinate for one year.

“The age pieces – imposed due to limited supplies and because the vaccine was considered less effective for people over the age of 80 years -” a normal experience. “

Scientists have been allowed to compare relatively equal groups: people who are qualified to vaccinate with a little older people who could not get it. “If you take 1,000 people born in one week and 1,000 people were born after one week, then there should be no difference between them, except for the big difference in absorbing vaccination,” said Dr. Gilsitzer.

The researchers follow the health records of about 280,000 people between the ages of 71 and 88 and without dementia when the operation began. Over the course of seven years, he received nearly half of those qualified to the vaccine, while only a small number of the unqualified group has been vaccinated, providing clear discrimination before and after.

To reduce the possibility of differences between groups, the researchers used the statistical analysis of data weight significantly from people only one week on both sides of the cut: those who reached 80 a week before the start of the operation and those who reached 80 in the following week.

They also examined the medical records of the potential differences between vaccination and non -fortified. They evaluated whether non -fortified people received more sheep diagnoses just because they visited doctors frequently, and whether they were taking more medications that may increase the risk of dementia.

“They are doing a good job in that,” said Dr. Gina, who He wrote a comment about the study for nature. “They look at approximately 200 drugs that have proven to be at least associated with the high risk of Alzheimer’s.”

He said: “They are doing a lot of effort to see whether or not there are other things that are timid with this age pieces, and any changes in other medical policy, and it does not seem so that.”

The study included an older form of logical impermissibility vaccine, Zostavax, which contains a modified version of the direct virus. Since then it has been suspended in the United States and some other countries because its protection against logical images has faded over time. The new vaccine, Shingrix, which contains an inactive part of the virus, appears more effective and durable.

Last year’s study Dr. Harrison and his colleagues have suggested that Chengerax may be more protection against dementia than the oldest vaccine. Based on a “other natural experience”, 2017 in the United States turned from Zostavax to Singrix, it was found that over six years, people who received the new vaccine had fewer dementia diagnoses than those who got the old. Among the people diagnosed with dementia, those who received the new vaccine had nearly six months more time before developing the situation more than the people who received the old vaccine.

There are different theories about the reason for protecting the logical imbalances from dementia. Dr. Gilsitzer said that by preventing shingles, vaccines reduce nervous inflammation caused by the reactivation of the virus. “Inflammation is bad for many chronic diseases, including dementia,” he said.

Both the new study and the Shingrix study provides support for that theory.

Another possibility is that vaccines raise the immune system on a wider scale. The new study provides some evidence of this theory as well. Dr. Gildesitzer said that he found that women, who have more interactive immune systems and more responses to antibodies to vaccination more than men, have witnessed greater protection against men’s dementia. The vaccine also had a greater preventive effect against dementia among people with autoimmune and allergic conditions.

Both theories may be correct. “There is evidence of the direct effect as well as an indirect effect,” said Dr. Nagil, who consulted the manufacturer of Singrix, GSK.

She said that some studies have found that other vaccines, including those against influenza, create a generalized nervous effect, but because the shingles virus is hiding in the nerves, it makes sense that the logic vaccine will be particularly protective against cognitive weakness.

Svetlana Okronva, a biologist in Duke, said, said Duke. A recent study On Alzheimer’s and other dementia and vaccines. She said that this may be because Alzheimer’s disease is related to the vulnerable immunity.

Dr. Gilsitzer said that the Welsh population in the study was mostly white, but the report also referred to similar preventive effects by analyzing death certificates in England due to deaths from dementia. His team also repeated the results in Australia, New Zealand and Canada.

Dr. Jenna said that the communication should be studied more and note that reducing the risk of dementia is not the same to prevent all cases. However, the evidence indicates that “something about exposure or access to the vaccine has this effect on the danger of dementia after years.”