Can aspirin a day maintain cancer? | Health news

For decades, aspirin was known as pain reliever. A new search for how to help this also help to fight cancer.

While previous research has been hinted at a link between the use of aspirin and the improvement of cancer survival, a Ticket Published in nature last week explains the reason. However, experts warn that aspirin is not a treatment – and it carries risks such as increasing the possibility of internal bleeding.

So, how can aspirin prevent cancer from spreading? What does this mean for future treatments?

What did studies find aspirin and cancer?

Recent studies have revealed how to help aspirin, a pain reliever widely used, The spread of cancer, Although it is unclear whether it will work as it is for all types of the disease.

The researchers were exploring this link for decades. the The first clinical studyAnd published in 1988, showed that the use of regular aspirin dramatically reduced the risk of colon and rectal cancer, although the main cause is unclear.

Now, a new study from Cambridge University offers more insight. I found the mechanism that may help aspirin by preventing cancer from spreading, a process known as a malignant tumor.

A malignant tumor is responsible for the majority Cancer deathsWith cancer cells from the original tumor and try the root elsewhere across the body.

Since these completed cancer cells wander, aspirin may enhance the body’s natural ability to fight, and keep the cancer cells to get more organs.

How can aspirin keep cancer from spreading?

The key to the effect of aspirin on cancer lies in the body’s immune system, which is a complex network of cells and proteins that defend infections, diseases and harmful germs.

When the cancer cells explode from the tumor, they enter the bloodstream, as the immune system usually fly-in a way that is identified by white blood cells known as T cells-to the bottom and destroyed them. However, platelets – small blood cell fragments that help in clotting – can interfere with this process.

Cancer benefit from platelets by running a similar response to the injury. When the platelets discover the free infection cancer cells, they rush to eagerness, and they will cover a wound to stop bleeding.

This creates a realistic shield, which makes it difficult for the immune system to identify and attack cancer cells. In addition, platelet release signals suppress the T cells, which prevents them from doing their work.

Aspirin disrupts cancer attempts to store by reducing the production of a molecule that platelets use to suppress immunotherapy. With weak platelets, T -cells restore their ability to identify and destroy cancer cells before they have an opportunity to form new tumors.

How can aspirin use against cancer?

The study indicates that aspirin can be used after treatments such as surgery where tumors are removed.

This is because some cancer cells have already escaped from the tumor and began to settle in other parts of the body, a process known as sowing, as small cancer cells include themselves in new areas and may later grow into tumors.

However, experts warn against using aspirin immediately as a cancer treatment without further research. The pain reliever carries the possibility of serious side effects such as internal bleeding because by weakening the platelets, it can weaken its ability to help the blood clot.

Aspirin prevents a molecule that stimulates the platelets of the bloc together. This makes blood thinner and increases the risk of uncontrolled bleeding. This is especially dangerous in the stomach, as aspirin can irritate the lining and cause ulcers, and in the brain, as it raises the risk of stroke bleeding if the small blood vessels explode.

In addition, the study was conducted on mice, not humans, so its effects on the spread of cancer should still be confirmed before recommending treatment.

“Our research provides a partial explanation for observations from clinical studies, but there is still a need to verify appropriate clinical health,” said Rahul Reoshodori, a professor at the Cambridge Pathology Department, who was part of the nature study.

There are many clinical experiences, such as the experience of additions in the United Kingdom, Ireland and India, Any patients It is likely to benefit more than taking aspirin and whether it works with specific types of cancer.

ROYCOUDHURI added that he does not expect an “fast -track translation” of aspirin to treat cancer.

Is aspirin used against diseases in the past?

Some patients with a high genetic risk of cancer, such as those with lynch syndrome (a condition that increases the possibility of developing some types of cancer), is already recommended to aspirin as a preventive measure in countries such as Australia and the United Kingdom.

Since the 1980s, aspirin has also been described for help Prevented heart attacks And strokes in people at risk of heart disease, by reducing the ability of platelets to form harmful clots that can prevent blood flow to the heart or brain. This impact on the stroke helps Reduce It is heart attacks in those who have a history of cardiovascular disease.

Does this mean that we are about to release cancer?

Not necessarily. While aspirin may help slow or prevent cancer, it does not completely remove tumors.

However, scientists work to identify vital indicators – blood -measurable signs – and platelet activity to help discover individuals at risk of developing cancer early.

“This would allow timely treatment with aspirin while reducing unnecessary exposure to those who do not request it,” said Paula Pattinani, a professor of pharmacology at the University of Gabriel Dznzio in Italy.

Experts say the results can also contribute to the development of medicines that prevent the spread of cancer.

“Our discoveries open possibilities for developing more targeted treatments that can provide benefits without the side effects of aspirin,” said Rewsudhi.

Patrenani, who is involved in research funded by cancer research in the UK to investigate whether other anti -platelets, such as Clubidogrell, provides similar benefits, says these studies will require completion from three to five other years.

However, she is optimistic about where the research is heading. We are about to be a great breakthrough in cancer research. This newly discovered knowledge can pave the way for innovative treatments and may save an endless life. “

Why is cancer treatment still far -reaching?

A treatment for cancer is still one of the biggest challenges in medicine.

Due to the presence of many different types of cancer, each of which has its properties and methods of spread, it is difficult to develop a global remedy.

In addition, the development of the tumor is affected by a range of genetic predisposition and environmental factors. studies Suggest This treatment should be dedicated to be really effective.

Many types of cancer are also evolving Ways to hide From or suppress the immune system, which makes it more difficult to attack even with immunotherapy.