A new snapshot of birth control turns into a long-term transplant-there is no required clinic

Planting contraceptives is a thin and flexible rod sitting under the skin and releasing birth control medications in the body for years. While it is one of The most effective forms of contraceptives And avoiding inconvenience to having to take birth control pills every day, the transplant requires a simple surgery, which can limit access. To make life a little easier, researchers create a self -combined birth control method that women can deal with with one injection.

A team of researchers has developed technology for self -operating birth control clips that work similar to the cultivation of contraceptives. As is detailed in a Ticket Monday was published in Nature Chemical Engineering, the shots will lead to a very effective and long -term contraceptive method for women who lack easy access to medical infrastructure. In addition, the design can be used to manage other long -term drugs, such as those with HIV.

This new approach provides hormonal drugs for pregnancy Lylororgstel through what researchers call “self -activated assemblies” (minimal). Once injected into the body, the small crystals gather in transplantation, or “warehouse” of the drug, which releases Levonorgestrel as it erodes for months or years.

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“The comprehensive goal is to give women the ability to access many different formats to prevent pregnancy that is easy to manage, compatible with its use in the developing world, and has a set of different time frames of work periods.” statement.

traditional Birth control clips It is already found and can be accessed more than transplanting birth control because patients can give themselves clips without the need to visit the hospital or a medical clinic. However, it is slightly less effective than transplantation, not long -term, so it should be managed every three months.

The design of the new contraceptive methods of researchers joins access to self -management clips with long -term transplant event. However, the challenge of SLIM self -management techniques was the large (and thus painful) needle to inject the drug. On the contrary, the team’s formula – Tiny crystals and solvents (in this case, allows a liquid compound called benzyl benzoate) – to use needles much smaller.

“The size of the needle and liquid wife is a decisive consideration of the commercial translation of injection,” said Giovanni Traversu, a great author of the digestive system specialist at the Massachusetts Institute of Technology, Jahram and the Women’s Hospital. statement. “Our engineering challenge was to find a way to increase comfort for patients using smaller needles, which cause less bruises or bleeding, and make the viscosity low enough to apply ease with the hand injection.”

Moreover, traverso and colleagues can adjust the mixture “to adjust the rate of drug launch, and expand its duration while preserving the injection,” the graduate student at the Massachusetts Institute of Technology in the Massachusetts Institute of Technology Institute explained. “This shows the possibility of connecting our system, which can be designed to meet a wide range of contraceptive needs as well as doses systems specifically designed for other therapeutic applications.”

While Slim has not passed through clinical trials yet, the development of technology in pre -clinical models paves the way for long -term long and effective drugs.